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November 5, 2015

RXi launches retinal anti-scar compound clinical trial

Courtesy of RXi Pharmaceuticals Corp.

RXi Pharmaceuticals of Marlborough said Thursday it has begun its first clinical trial of a compound to evaluate its ability to prevent retinal scarring.

The study will evaluate the safety of RXI-109 as well as its ability to prevent the progression of retinal scarring, a harmful consequence of several eye diseases. The study will use subjects with advanced neovascular, age-related macular degeneration.

RXi Pharmaceuticals focuses on research in dermatology and ophthalmology.

The company describes RXI-109 as a self-delivering compound developed to target connective tissue growth factor, a key regulator of scar formation in the skin and known to be involved in retinal scarring. RXI-109 is also currently being evaluated in clinical dermatology trials.

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